Controller

Aphios Corporation

Boston, MA Area | Fractional | Consulting

Job Code: APH-2605

Aphios Corporation, a clinical-stage biotechnology company, is seeking an experienced Fractional Controller to strengthen our accounting, financial reporting, internal controls, and audit readiness as we advance clinical programs, strategic partnerships, financing activities, and our longer-term path toward the public markets.

This is a hands-on senior accounting role for an experienced Controller, Assistant Controller, CPA, or senior accounting professional who can operate effectively in an entrepreneurial biotechnology environment while helping establish the financial discipline and reporting infrastructure expected of a growing, pre-IPO company.

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Key Responsibilities

• Maintain accurate general ledger and financial reporting
• Manage monthly, quarterly, and annual close processes
• Prepare financial statements in accordance with U.S. GAAP
• Oversee reconciliations, AP/AR, payroll coordination, cash reporting, and budget-to-actual analysis
• Maintain and strengthen accounting policies, documentation, and internal controls
• Maintain and improve Sage, or help implement an appropriate scalable accounting/ERP system
• Prepare financial schedules and supporting documentation for independent audits
• Maintain GAAP-compliant, audit-ready financial records
• Support accounting and financial diligence for financings, strategic partnerships, and corporate transactions
• Help build accounting and reporting practices appropriate for potential future SEC and public-company requirements
• Support accounting across Aphios Corporation and affiliated entities as appropriate

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Qualifications

Required:

• Bachelor's degree in Accounting, Finance, or related discipline
• Significant hands-on accounting and financial reporting experience
• Strong practical knowledge of U.S. GAAP
• Experience with Sage or comparable accounting/ERP systems
• Experience supporting independent financial audits
• Ability to work independently in an entrepreneurial environment

Highly Desirable:

• CPA or equivalent senior accounting credentials
• Biotechnology, pharmaceutical, or life-sciences accounting experience
• NIH/SBIR/STTR or federal grant accounting experience
• Pre-IPO or public-company accounting experience
• SEC reporting and SOX/internal-control experience
• Audit Committee interaction
• Equity and capitalization accounting
• Experience supporting IPOs, direct listings, reverse mergers, SPACs, or other public-market transactions

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About Aphios

Aphios is advancing a diversified therapeutic portfolio that includes a planned Phase 3 clinical program for Zindol®, planned Phase 2b programs in opioid addiction and chronic epilepsy, and additional therapeutic programs progressing through IND-enabling development.

We combine clinical-stage assets with proprietary pharmaceutical and nanotechnology platforms and are pursuing strategic partnerships, institutional financing, and longer-term public-market opportunities.

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How to Apply

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